To express curses upon (somebody), when irked or wroth, as though wishing someone "a pox".
A pox o' your throat, you bawling, blasphemous, incharitable dog!
To hell with (abstract or unalive things).
A pox of that jest! and I beshrew all shrows.
Originally an expression of abuse to wish that someone develop pocks, that is to say, contract pox. Though pox can range from smallpox to chickenpox to cowpox to syphilis, this expression almost alway...
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