Used other than figuratively or idiomatically: see blow, up.
See if you can blow the bubbles up the staircase.
To explode or be destroyed by explosion.
Why do cars in movies always blow up when they fall off a cliff?
To cause (something or someone) to explode, or to destroy (something) or maim or kill (someone) by means of an explosion.
From Middle English blow up, blowe up, dissimilated forms of earlier Middle English upblowen (> English upblow), equivalent to blow + up. Compare West Frisian opblaze (“to blow up, inflate”), Dutch op...
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We had to blow up the bridge before the enemy army arrived.