An embarrassing feeling that leaves a person confused.
Prophet of o'er-population, your ingenious calculation, Causeth discombobulation only in the anxious mind
A confused or disorderly state.
What has changed since the time of Looney Tunes is the discombobulation of characters' faces. Eyeballs constantly bulge beyond normal proportion to show shock or jubilation; cheeks shrink, sag or even bend in shame, fatigue or anger. Each emotion is heightened, overemphasized with cubist contortions.
From discombobulate + -ion.
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