In a direction away from the speaker or other reference point.
He drove off in a cloud of smoke.
Into a state of non-operation or non-existence.
Please switch off the light when you leave.
So as to remove or separate, or be removed or separated.
He bit off the end of the carrot.
Not positioned upon, or away from a position upon.
He's off the roof now.
Detached, separated, excluded or disconnected from; away from a position of attachment or connection to.
The phone is off the hook
To kill.
Most sorely missed is the relationship between Eggsy and Colin Firth’s delightfully avuncular mentor figure Harry Hart, who was offed, seemingly definitively with a bullet to the brain towards its end.
To switch off.
Beginning; starting point.
He has been very obviously an untrustworthy narrator right from the off.
From Middle English of, from Old English of, af, æf (“from, off, away”), from Proto-West Germanic *ab, from Proto-Germanic *ab (“from”), from Proto-Indo-European *h₂epo (“from, off, back”). Doublet of...
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Cancelled; not happening.
The party's off because the hostess is sick.
Not fitted; not being worn.
Your feet will feel better once those tight boots are off.
Outside the area or region of.
The suspect is now believed to be off the campus.
Can you off the light?