Of animals, plants, or substances: extremely venomous or poisonous.
Extremely hostile or malicious; intensely acrimonious.
The politicians were virulent in their hatred of the president.
Of a disease or disease-causing agent: malignant, able to cause damage to the host.
PIE word *wisós From Middle English virulent (“leaking or seeping pus, purulent; (of putrefaction) extremely severe (sense uncertain)”) [and other forms], borrowed from Latin vīrulentus (“poisonous”)...
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